Search on: NEURAL TUBE DEFECTS 
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Descriptor English:   Neural Tube Defects 
Descriptor Spanish:   Defectos del Tubo Neural 
Descriptor Portuguese:   Defeitos do Tubo Neural 
Synonyms English:   Craniorachischisis
Developmental Defects, Neural Tube
Diastematomyelia
Exencephaly
Neurenteric Cyst
Spinal Cord Myelodysplasia
Tethered Cord Syndrome  
Tree Number:   C10.500.680
C16.131.666.680
Definition English:   Congenital malformations of the central nervous system and adjacent structures related to defective neural tube closure during the first trimester of pregnancy generally occurring between days 18-29 of gestation. Ectodermal and mesodermal malformations (mainly involving the skull and vertebrae) may occur as a result of defects of neural tube closure. (From Joynt, Clinical Neurology, 1992, Ch55, pp31-41) 
Indexing Annotation English:   do not confuse entry term SPINAL CORD MYELODYSPLASIA with MYELODYSPLASTIC SYNDROMES, a defect of bone marrow formation
History Note English:   1979; for DIASTEMATOMYELIA and TETHERED CORD SYNDROME use SPINA BIFIDA OCCULTA 1991-1999; for NEURENTERIC CYST use SPINA BIFIDA OCCULTA 1991-1999, use NEURAL TUBE DEFECTS 1979-1990 
Allowable Qualifiers English:  
BL blood CF cerebrospinal fluid
CI chemically induced CL classification
CO complications DI diagnosis
DH diet therapy DT drug therapy
EC economics EM embryology
EN enzymology EP epidemiology
EH ethnology ET etiology
GE genetics HI history
IM immunology ME metabolism
MI microbiology MO mortality
NU nursing PS parasitology
PA pathology PP physiopathology
PC prevention & control PX psychology
RA radiography RI radionuclide imaging
RT radiotherapy RH rehabilitation
SU surgery TH therapy
US ultrasonography UR urine
VE veterinary VI virology
Record Number:   9629 
Unique Identifier:   D009436 

Occurrence in VHL:
 

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